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Studies have shown that activation of the Nrf2/HO-1 pathway contributes to cisplatin resistance

Moreover, it downregulates the protein levels of cell proliferation marker PCNA, decreases cell viability and number, and upregulates the protein levels of pro-apoptotic markers [91]

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Glutathione exerts its skin-lightening effect through multiple pathways: it inhibits the enzyme tyrosinase, which is the rate-limiting enzyme in melanin synthesis

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Reconstitution technique may have compromised potency